The following information was taken from an article written by PartyBoy from Muscle Talk – Original post here
Clenbuterol is a multipurpose drug. As a beta-receptor and bronchodilator that acts as a stimulant and is beneficial to people who have asthma. The drug opens the airways making it much easier for asthma sufferers to breathe and remain calm. It also has anti-catabolic and thermogenic properties that are beneficial to body builders and people who are trying to lose weight.With the right Clenbuterol dosage, it can be a great performance enhancer and can improve an athlete’s workout routine making it more efficient and more productive.
Depending on what clenbuterol is being used for, the dosage will vary according to specific pieces of information. Clen dosages for men and women normally vary due to the differences in their metabolism and their overall level of activity. The dosage given will also be determined by what it is to be used for. When clenbuterol is prescribed for weight loss, the amount will different than what is prescribed to someone who needs to use it as a bronchodilator.
Athletes and bodybuilders use the drug due to its thermogenic and anti-catabolic effects. This is down to its ability to slightly increase the body’s core temperature, thereby raising calorie (energy) expenditure. It is thought that a 1°F increase yields around a 5% increase in maintenance calories burned. Studies on livestock suggest that clenbuterol also has anabolic properties. However, this seems not to be the case in humans, thought to be due to the fact that humans lack the abundance of beta 3 receptors which increase insulin production and sensitivity.
Clenbuterol is dosed in micrograms (mcg/µg), most commonly in tablet form, though there are other forms of administration such as liquids, nasal sprays and injectables. Note: Although dosages are in microgram amounts, many manufacturers will list the active ingredient as milligrams (mg), so a tablet of 20mcg will be labelled as 0.02mg.
More information regarding the science of fat loss agents can be found here.
- Post-Cycle Therapy: Clen is used post cycle to aid in recovery. It allows the user to continue eating large amounts of food, without worrying about adding body fat. It also helps the user maintain more of his strength as well as his intensity in the gym. Diet: Roughly the same as on cycle.
- Fat loss: The most popular use for Clen, it also increases muscle hardness, vascularity, strength and size on a caloric deficit. For the most significant fat loss, Clen can be stacked with T3.
- Alternative to Steroids: Clenbuterol has mild steroid-like properties and can be used by non AS using bodybuilder to increase LBM as well as strength and muscle hardness.
- Stimulant/Performance Enhancement: It can be used as a stimulant, but an ECA stack may be a better choice because of it’s much shorter half-life.
Pharma, UGL or Liquid?
Having tried and tested all 3 I would definitely recommend using pharmaceutical grade Clen. Clen is measured in micro grams (mcg) and I believe underground labs have a difficult time dosing their clenbuterol accurately as the equipment required to split raw powder in to micro gram-accurate tablets or capsules is expensive. When I used D-Hacks clenbuterol in the past, even at doses as low as 40mcg per day I felt awful and had tons of bad side effects. With pharmaceutical grade Clen I have been able to gradually taper my dose to upwards of 100mcg without any bad side effects. Precise dosing is very important with this drug in my opinion, that’s why I’ll always opt for pharma. I have used the Bulgarian pharmacy brand ‘Sopharma’ multiple times with good results, there are fakes around so do your homework before spending any money on bunk Clen.
Common side effects of Clenbuterol include:
- Muscular tremors (especially hand shakes)
- Muscular cramps
- Increased appetite
- Hypertension (high blood pressure)
- Possible cardiac hypertrophy as clen also targets cardiac and smooth muscle fibres
Heart muscle necrosis has been demonstrated in animal studies
In view of the above side effects, it is obvious to assume that anyone with cardiac issues and/or hypertension should not use a stimulant such as Clenbuterol and caution must be observed by those already using similar compounds in the treatment of existing medical conditions. In addition, there is very little conclusive knowledge of the cardiac effects of supra-physiological dosages in humans.
Cramping whilst using Clenbuterol is a fairly common side effect. This is most probably due to depletion of the amino acid taurine in the liver together with deficits in the electrolytes sodium and potassium, as well as inadequate hydration. Taurine helps stabilize cell membranes and prevent nerves from becoming over-excited. Some studies show that giving taurine supplements relieves painful muscle cramps. Japanese researchers found that the longer rats exercised, the more taurine they lost from their muscles
Symptoms of cramping may be alleviated by:
- Eating fruit particularly bananas
- Ensuring adequate hydration
- Taurine supplementation – 3-5g daily
- Potassium supplementation – 200-400mg daily taken before bed on an empty stomach
Men: Taper up to 140mcg per day
Women: Taper up to 80-100mcg per day
For the first cycle I would always go with a tapering approach. It gives you a chance to assess your tolerance, some people feel awful even on low doses of Clen so jumping right in to a high dose of 100mcg+ is not a good idea. I would recommend starting at around 40mcg and tapering up by 20mcg every few days until you have reached your desired dose. For your second and third cycle you will have an understanding of where your tolerance sits and won’t have to start off on such a low dose.
There is no particular requirement to split the dosage throughout the day due to the long half life. Most will take the full daily dose in the morning, though some prefer to take their dose just before bed in an attempt to avoid most of the side effects as they sleep.
There are a number of methods that are often recommended online – the most common methods are 2 days on, 2 days off and 2 weeks on, 2 weeks off.
A tapering up of dosages is recommended in an attempt to limit harsh side effects. Most commonly, a user will start by taking one 20mcg tablet on day 1, followed by an increase of one tablet on subsequent days. Subject to personal tolerance levels, a dosage of 140mcg (seven tabs) will be used by day 7, and this level should be maintained for the entire second week. It would be fruitless to exceed seven or eight tablets daily due to receptor over-saturation. There is no requirement to taper down.
For the next ‘cycle’ of clen (i.e. weeks 5 & 6), there is no requirement to taper up from one or two tablets as your tolerance level should now be known. As an example, if the user finished the first cycle of clen on 7 tabs, they could recommence at a slightly lower dose of 4 or 5, and taper up again from this level. Again though, the user should again limit their intake to 7 or 8 tabs daily.
Below is an outline of what a 2 weeks on, 2 weeks off cycle might look like.
During the two ‘off’ weeks, an ECA stack can be used as required. ECA will not cause such a pronounced down regulation and desensitization of the receptors, certainly not to the extent of clen. Ephedrine has a short half life in contrast to clen which results in times throughout the day where the betas will partially recover from stimulation by adrenaline and nor-adrenaline. Potency is also much weaker that that of clen, as it is not a specific agonist. Ephedrine is also thought to increase the conversion of endogenous/exogenous T4 to T3 through the activation of deiodinase enzymes responsible for this process. This is important as clen is known to slow the rate of T4 to T3 conversion. As a side note, some bodybuilders will use T3 concurrently with the Clenbuterol/ECA cutting cycle (together with certain anabolic/androgenic steroids no doubt!) in an attempt to at least maintain plasma T3 levels.
Ketotifen is an anti-histamine used medically to treat bronchial asthma and allergies. It has a sedative and depressant effect on the brain. It acts by decreasing the release of histamine which is a chemical released when an allergic reaction occurs. Ketotifen blocks the action of histamine on special histamine receptors and reduces the nerve response when an allergic reaction occurs.
Histamine is the chemical in the body that causes the symptoms of an allergic (hypersensitivity) reaction. These can include inflammation of the skin, airways or tissues, rashes, itching and of the skin, eyes or nose, nasal congestion and narrowing of the airways. By blocking the actions of histamine, ketotifen may prevent and relieve the narrowing of the airways that occurs in asthma due to allergies.
However, bodybuilders are interested in the drug as it has been shown to inhibit the down regulation of the beta receptors, including the beta 2s that clen stimulates. As long as you are taking ketotifen, it will continue to clean these receptors, never allowing them to downregulate, even while on a heavy clen cycle. That means you can continue to take clen indefinitely without having to cycle off to regenerate the receptors. A dose of 2-3mg daily can upregulate even severely shut down receptors within a week.
It also means that you don’t need as much clen to get the same benefits. It seems you can take about 30-40% less clen and it be equally effective.
No studies have been done to find the most effective dose though most users should find 3-4mg daily ideal, which can be split or taken in one sitting. Higher doses are likely to cause (sometimes severe) drowsiness and increase appetite.
I use email@example.com – they stock pharmaceutical grade Clenbuterol. Shipping to the UK usually takes 1-2 days and they do ship internationally too. Just send them an email explaining that you got their email address from this website and ask for a price list and they will send over a full list of products and prices.